For seven glorious minutes, that magnificent, buoyant, vocal 7,800-strong Plymouth support, who made the 560-mile round trip north knowing they would not be back home until the early hours of Sunday morning, dared to dream. Maksym Talovierov, a 24-year-old January signing from LASK, whose parents live in Ukrainian capital Kyiv, had headed in Matthew Sorinola's corner and looked to the skies in celebration as Argyle's fans celebrated. After knocking out Premier League leaders Liverpool in the fourth round, were they about to beat another of English football's giants in the fifth? With a little help from skipper Kevin de Bruyne, O'Reilly decided not. In first-half stoppage time, De Bruyne, who since his debut in the competition in January 2016 has been involved in more FA Cup goals than anyone else, curled in a brilliant free-kick that O'Reilly headed home. Then, 14 minutes from time, after Plymouth goalkeeper Conor Hazard had produced a brilliant double save to deny Erling Haaland and Bernardo Silva, O'Reilly was on hand at the far post to nod home Phil Foden's corner. The goal was a shattering blow for Plymouth, whose hopes were ended in the final minute when De Bruyne turned home Haaland's low cross from four yards. The result confirmed City's status as overwhelming favourites for the game and keeps Pep Guardiola in the hunt for a third victory in a tournament he "loves". But the Plymouth fans can take pride in their team's performance on that long trip home, having backed them to the hilt with their magnificent support. "We created a lot and conceded little – the basics we have done for many years," Guardiola told BBC Sport. "We're happy to reach the quarter-finals and with the way we played. "How many times in the last years have we reached the semi-finals? When you arrive six times in a row in the semi-finals, it's because [the FA Cup] is important. When you play in this competition and you behave like the way we behave, I'm so proud – I love it. "We're one game away from Wembley and we'll see what happens."

Vincent Kompany's side fell behind in the first half when ex-Bayern youngster Angelo Stiller drove a fine finish into the top corner after the hosts capitalised on a slip by Leroy Sane. But Sane recovered from that to set up the equaliser, sending Michael Olise through on goal to finish on the stroke of half-time. Leon Goretzka then put Bayern ahead midway through the second half when he won possession high up before firing past Alexander Nubel, before Kingsley Coman struck in stoppage time to wrap up the win. The win means Bayern move 11 points clear of Bayer Leverkusen at the top of the table. Leverkusen are Eintracht Frankfurt on Saturday.

The visitors, who sit second in La Liga, went ahead when Kylian Mbappe picked out Ferland Mendy, who squared for Brahim Diaz to slot into an empty net from close range. Madrid had a couple of chances to double their lead before Johnny Cardoso equalised with a 34th-minute header from Isco's corner. Isco - captaining Betis against the club where he spent nine years - then netted a 54th-minute penalty after Antonio Rudiger had fouled Jesus Rodriguez in the box. The hosts almost got a third when Cucho Hernandez shot wide after being picked out by Manchester United loanee Antony, who was available after his side won an appeal against his red card last week. Betis, managed by ex-Madrid and Manchester City boss Manuel Pellegrini, move up to sixth in the La Liga table and fully deserved their victory with 18 shots to Madrid's nine. It was the fourth time this season Carlo Ancelotti's side have lost in La Liga and they remain behind Barcelona on goal difference.

The former Manchester City forward ran on to a superb defence-splitting ball by Marcos Llorente before calmly slotting in to break the deadlock in the 66th minute. Athletic Club came agonisingly close to an equaliser when Benat Prados headed against the post and Inaki Williams crashed the rebound off the underside of the crossbar. Diego Simeone's Atletico knew a win over the Bilbao side would see them jump above both Barcelona and Real Madrid, who lost to Real Betis earlier on Saturday. However, their two-point lead could be short-lived, with second-placed Barcelona playing their game in hand against Real Sociedad on Sunday. Atletico will hope they can rub more salt in the wounds of city rivals Real Madrid when they face each other in the first leg Champions League last 16 on Tuesday.

The hosts always looked in control but found visiting goalkeeper Ethan Horvath in fine form as he made several key saves to keep Cardiff competitive. In a game of attack versus defence, the hosts struggled to breakdown Cardiff's low block, but eventually found the breakthrough when Marco Asensio swept the ball home from Marcus Rashford's precise cross. Asensio made the result safe on 80 minutes as he converted from Leon Bailey's cross with another pinpoint finish as he scored his fourth goal since arriving on loan from Paris St-Germain in January.