Sweden forward Isak has endured a bitterly frustrating spell since completing a British record £125m move from Newcastle. But he set Liverpool on their way to a third straight top-flight win when his shot into the ground from 12 yards looped over the head of Palace goalkeeper Dean Henderson and into the net. Liverpool's third-choice keeper Freddie Woodman made his first Premier League appearance for the Reds as Alisson and Giorgi Mamardashvili were both injured. Woodman made a diving save to keep out Jean-Philippe Mateta's header moments before Liverpool made it 2-0 through Andy Robertson. The Scotland full-back finished off a fine counter-attack with a precise finish following a lightning attack involving Curtis Jones. Palace set up a grandstand finish when Daniel Munoz scored from outside the box with Woodman down injured, before Eagles substitute Jorgen Strand Larsen hit the post in the 84th minute. But the Reds sealed victory through Florian Wirtz deep into stoppage time, a right-foot finish from inside the box.

West Ham's dramatic 2-1 win over Everton left Spurs two points from safety, third from bottom with four games remaining. Roberto de Zerbi's side looked like climbing out of the drop zone after substitute Palhinha prodded in from close range at already relegated Wolves only for Callum Wilson's strike to earn the Hammers an injury-time victory in their match. The drama was not restricted to the London Stadium as Antonin Kinsky produced a brilliant last-gasp save to keep out Joao Gomes' free kick. Spurs, who are trying to avoid a first top flight relegation since 1977, also lost Dominic Solanke and Xavi Simons to injury. The nerves from the visitors were obvious as they looked for a first top-flight win since December but they still dominated a forgettable first half, although desperately lacked quality. They had little to build on at the break and Simons wasted a good chance when he fired over after skipping past Matt Doherty before he was carried off with a knee injury. Jose Sa's fine stop denied Rodrigo Bentancur but Palhinha forced in the winner with seven minutes left and Kinsky's injury-time save from Joao Gomes sealed victory.

Vincent Kompany's men were 3-0 down at the break after the Bayern boss made nine changes from the midweek win over Bayer Leverkusen in the German Cup semi-finals, with the Bundesliga title already secured following last weekend's win over Stuttgart and with Tuesday's Champions League last-four first-leg clash with Paris St-Germain in mind. But he threw on Harry Kane and Michael Olise at the interval before Jamal Musiala also came on early in the second half and all three helped complete the remarkable turnaround. Dominik Kohr scored a tidy volley in the 15th minute from a Kaishu Sano cross to put Mainz O5 into an early lead before Paul Nebel turned home a rebound from Nadiem Amiri's saved effort. Sheraldo Becker tapped home in first-half stoppage time after Amiri had a strike tipped on to the bar by Bayern back-up keeper Jonas Urbig and it looked like the upset was on with Bayern heading for just their second league defeat of the season. But on-loan striker Nicolas Jackson started the comeback when he turned home Konrad Laimer's cross seven minutes after the restart before ex-Crystal Palace winger Olise scored a stunning second after he cut inside off the left before curling the ball into the top corner in the 73rd-minute. Olise was involved for the equaliser as he put the ball in for Musiala, who managed to bundle it over the line with 10 minutes remaining. Kane completed the turnaround in the 83rd minute after Musiala's cross was pushed into his path by Mainz 05 keeper Daniel Batz. Mainz 05, who were bottom of the Bundesliga after 13 games when head coach Urs Fischer was appointed in December, will have to wait another week to ensure they are mathematically safe from relegation as they remain eight points clear of the drop zone with three games to go.

Alvaro Arbeloa's side, playing for the first time since being knocked out of the Champions League quarter-finals by Bayern Munich, ended a run of two league games without a win. But Barca have the chance to reinstate their nine-point lead on Wednesday evening when they host Celta Vigo, with just six games to go. Real are on course for only their fifth trophyless season this century - 2004-05, 2005-06, 2009-10, and 2020-21 being the only four. But with Arbeloa's future reportedly uncertain, winning La Liga may be the only way he keeps his job for next season. It was French striker Mbappe who opened the scoring at the Bernabeu in the 30th minute, with a smart finish for his 24th league goal of the season. Six minutes into the second half, Brazil winger Vinicius doubled Real's lead. He latched onto Federico Valverde's pass to smash into the bottom corner for his 12th of the campaign. Alaves halved the deficit with the last kick of the game through strikerTony Martinez netted. Real still have to travel to Barcelona in May for La Liga's second El Clasico of the season, but are relying on Hansi Flick's leaders to slip up elsewhere. Up next for Real is a trip to Real Betis on Friday night, while Alaves host Mallorca a day later.

Goals from Ferdi Kadioglu, Jack Hinshelwood and Danny Welbeck lifted Brighton into sixth place, while Chelsea have now lost five consecutive league matches without scoring for the first time since 1912. Brighton overwhelmed Chelsea in the opening stages of the match. Kaoru Mitoma almost replicated his goal at Tottenham last weekend, volleying Pascal Gross' shot first time, only for Robert Sanchez to make the save inside the opening two minutes. Brighton then scored from the resulting corner when Kadioglu struck a low volley after capitalising on a loose attempted clearance by Jorrel Hato from Gross' delivery in the third minute. The chances kept coming for the hosts. Jan Paul van Hecke's header was saved, Hinshelwood had an effort cleared off the line after a calamitous wayward pass from Sanchez, while Georginio Rutter fired over when from inside the box. Chelsea were eventually punished again, as Hinshelwood made amends by sweeping home Brighton's second goal in the 56th minute from Rutter's pass. Such was the one-way traffic, Chelsea managed just one attempt of any kind in the opening 40 minutes - a speculative, blocked effort from Trevoh Chalobah on the edge of the box. Chants of "we've had a shot" followed from the away supporters after Romeo Lavia fired wide shortly after half-time, before frustration turned towards head coach Rosenior. There were late attempts from Alejandro Garnacho and fellow substitute Marc Guiu, who both fired wide late on, but Brighton could have scored more in the second half through two saved Kadioglu shots. And they did get a third when two subsitutes combined down the left, with Maxim de Cuyper feeding Welbeck to fire home his 13th goal of the season into the roof of the net. It was a memorable night for the in-form Seagulls, who moved above Chelsea into sixth place, while the Blues look increasingly unlikely to qualify for the Champions League and could drop into the bottom half of the table once all fixtures this round have been completed.